Itaconate and NLRP3 Inflammasomes

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Metformin inhibition of mitochondrial ATP and DNA synthesis abrogates NLRP3 inflammasome activation and pulmonary inflammation

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KIM-1 mediates fatty acid uptake by renal tubular cells to promote progressive diabetic kidney disease

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beta-2-microglobulin triggers the NLRP3 inflammasome in macrophages to promote multiple myeloma

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